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Which type of lesion contains clear fluid and is often very small?

  1. Vesicle

  2. Macule

  3. Patch

  4. Lesion

The correct answer is: Vesicle

A vesicle is a small, fluid-filled sac that is typically less than 1 centimeter in diameter. These lesions are often seen in various dermatological conditions, such as herpes simplex virus infections or contact dermatitis, where they can present as blisters containing clear serous fluid. The defining characteristic of a vesicle is its small size and the presence of clear fluid, which differentiates it from other types of skin lesions. In contrast, a macule is a flat, discolored spot on the skin that does not involve any elevation or fluid, while a patch is larger and also flat but typically has a different texture or elevation compared to macules. The term "lesion" is a more general category that encompasses any abnormal tissue change on the skin or body, including vesicles, macules, and patches. Thus, the specific attributes of a vesicle match the description of containing clear fluid and being very small.