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Which of the following is NOT a term used to refer to the second layer of the skin?

  1. Dermis

  2. Epithelium

  3. Subcutaneous layer

  4. Stratum corneum

The correct answer is: Epithelium

The term not used to refer to the second layer of the skin is "Epithelium." In the structure of the skin, the epithelium typically refers to the outermost layer known as the epidermis. It consists of several layers, including the stratum corneum, which is the outermost part of the epidermis. The dermis, on the other hand, is indeed the second layer of the skin lying beneath the epidermis. It contains connective tissue, blood vessels, and nerve endings. The subcutaneous layer, also known as the hypodermis, sits below the dermis and primarily consists of fat and connective tissue, providing insulation and cushioning. The stratum corneum is part of the epidermis and plays a significant role in protecting the underlying layers of skin. Therefore, identifying epithelium as the term not associated with the second layer highlights an understanding of the skin's layered structure.